Rapid diagnosis of pedal osteomyelitis in diabetics with a technetium-99m-labeled monoclonal antigranulocyte antibody

Both the Moab and WBC images show focally increased activity in the right great toe of a 54-year-old woman with biopsy examination-proven osteomyelitis of this digit.

All 3 studies are false positive for osteomyelitis in a 53-year-old man with a pedal ulcer underlying the right great toe. Bone biopsy examination revealed no evidence of osteomyelitis. Interpreting the bone images with either the Moab or WBC does not change their interpretation.

The Moab study is true negative, whereas the WBC study is false positive in a 74-year-old man with a pedal ulcer underlying the left first metatarsal bone. Left lower extremity amputation revealed gangrene but there was no evidence of osteomyelitis. When the WBC images were read in conjunction with the bone scan, the study was classified correctly as negative. The Moab results are unchanged.

The Moab is true positive and the WBC is false negative in a 62-year-old woman with biopsy examination-proven osteomyelitis of the fourth metatarsal of the right foot. The addition of the bone images does not alter the interpretation of either the Moab or WBC.