Journal of Foot and Ankle Surgery
Volume 48, Issue 6 , Pages 690.e7-690.e11 , November 2009

Bizarre Parosteal Osteochondromatous Proliferation of the Metatarsal: A Pediatric Case Report and Archival Review

  • Kar Hao Teoh, MBChB

      Affiliations

    • Foundation Doctor, Department of Orthopaedic Surgery, Royal Hospital for Sick Children, Edinburgh, UK
    • Corresponding Author InformationAddress correspondence to: Kar Hao Teoh, MBChB, Department of Orthopaedic Surgery, Royal Hospital for Sick Children, Sciennes Road, Edinburgh EH9 1LF, UK.
    • ,
  • Nicholas Shortt, FRCSEd (Tr & Orth)

      Affiliations

    • Orthopaedic Specialist Registrar, Department of Orthopaedic Surgery, Royal Hospital for Sick Children, Edinburgh, UK
    • ,
  • Graham Wilkinson, FRCR

      Affiliations

    • Consultant Radiologist, Department of Radiology, Royal Hospital for Sick Children, Edinburgh, UK
    • ,
  • Donald M. Salter, FRCPath

      Affiliations

    • Professor of Osteoarticular Pathology and Consultant Histopathologist, Department of Pathology, Royal Infirmary of Edinburgh, Edinburgh, UK
    • ,
  • James E. Robb, MD, FRCS

      Affiliations

    • Consultant Orthopedic Surgeon, Department of Orthopaedic Surgery, Royal Hospital for Sick Children, Edinburgh, UK
    • ,
  • Daniel E. Porter, MD FRCS (Tr & Orth)

      Affiliations

    • Senior Lecturer and Honorary Consultant Orthopaedic Surgeon, Department of Orthopaedic Surgery, Royal Hospital for Sick Children, Edinburgh, UK

References 

  1. Nora FE, Dahlin DC, Beabout JW. Bizarre parosteal osteochondromatous proliferations of the hands and feet. Am J Surg Pathol. 1983;7:245–250
  2. Sundaram M, Wang L, Rotman M, Howard R, Saboeiro AP. Florid reactive periostitis and bizarre parosteal osteochondromatous proliferation: pre-biopsy imaging evolution, treatment and outcome. Skeletal Radiol. 2001;30:192–198
  3. Dorfman HD, Czerniak B. Bone Tumors. Mosby, St Louis, MO 1120–1194, 1998.
  4. Endo M, Hasegawa T, Tashiro T, Yamaguchi U, Morimoto Y, Nakatani F, et al. Bizarre parosteal osteochondromatous proliferation with a t(1;17) translocation. Virchows Arch. 2005;447:99–102
  5. Nilsson M, Domanski HA, Mertens F, Mandahl N. Molecular cytogenetic characterization of recurrent translocation breakpoints in bizarre parosteal osteochondromatous proliferation (Nora's lesion). Hum Pathol. 2004;35:1063–1069
  6. Abramovici L, Steiner GC. Bizarre parosteal osteochondromatous proliferation (Nora's lesion): a retrospective study of 12 cases, 2 arising in long bones. Hum Pathol. 2002;33:1205–1210
  7. Meneses MF, Unni KK, Swee RG. Bizarre parosteal osteochondromatous proliferation of bone (Nora's lesion). Am J Surg Pathol. 1993;17:691–697
  8. Torreggiani WC, Munk PL, Al-Ismail K, O'Connell JX, Nicolaou S, Lee MJ, et al. MR imaging features of bizarre parosteal osteochondromatous proliferation of bone (Nora's lesion). Eur J Radiol. 2001;40:224–231
  9. Rybak LD, Abramovici L, Kenan S, Posner MA, Bonar F, Steiner GC. Cortico-medullary continuity in bizarre parosteal osteochondromatous proliferation mimicking osteochondroma on imaging. Skeletal Radiol. 2007;36:829–834
  10. Helliwell TR, O'Connor MA, Ritchie DA, Feldberg L, Stilwell JH, Jane MJ. Bizarre parosteal osteochondromatous proliferation with cortical invasion. Skeletal Radiol. 2001;30:282–285
  11. Yuen M, Friedman L, Orr W, Cockshott WP. Proliferative periosteal processes of phalanges: a unitary hypothesis. Skeletal Radiol. 1992;21:301–303
  12. Zambrano E, Nose V, Perez-Atayde AR, Gebhardt M, Hresko MT, Kleinman P, et al. Distinct chromosomal rearrangements in subungual (Dupuytren) exostosis and bizarre parosteal osteochondromatous proliferation (Nora lesion). Am J Surg Pathol. 2004;28:1033–1039
  13. Jean-Loup Huret. Atlas of Genetics and Cytogenetics in Oncology and Haematology. Last update: 5 January 2008. Available at: http://atlasgeneticsoncology.org/. Accessed June 12, 2009.
  14. Choi JH, Gu MJ, Kim MJ, Choi WH, Shin DS, Cho KH. Fibrosarcoma in bizarre parosteal osteochondromatous proliferation. Skeletal Radiol. 2001;30:44–47

 Financial Disclosure: None reported.

 Conflict of Interest: None reported.

PII: S1067-2516(09)00284-1

doi: 10.1053/j.jfas.2009.06.012

Journal of Foot and Ankle Surgery
Volume 48, Issue 6 , Pages 690.e7-690.e11 , November 2009

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