Journal of Foot and Ankle Surgery
Volume 48, Issue 6 , Pages 668-671 , November 2009

Complications Associated with Autogenous Bone Marrow Aspirate Harvest from the Lower Extremity: An Observational Cohort Study

  • Thomas S. Roukis, DPM, PhD, FACFAS

      Affiliations

    • Chief, Limb Preservation Service, Vascular/Endovascular Surgery Service, Department of Surgery, Director Limb Preservation Complex Lower Extremity Surgery and Research Fellowship, Madigan Army Medical Center, Tacoma, WA
    • Corresponding Author InformationAddress correspondence to: Thomas S. Roukis, DPM, PhD, FACFAS, Chief, Limb Preservation Service, Vascular/Endovascular Surgery Service, Department of Surgery, Director Limb Preservation Complex Lower Extremity Surgery and Research Fellowship, Madigan Army Medical Center, 9040-A Fitzsimmons Drive, MCHJ-SV, Tacoma, WA 98431.
    • ,
  • Christopher F. Hyer, DPM, FACFAS

      Affiliations

    • Director, Advanced Foot & Ankle Surgery Fellowship, Orthopedic Foot & Ankle Center, Columbus, OH
    • ,
  • Terrance M. Philbin, DO

      Affiliations

    • Director, Orthopedic Foot & Ankle Fellowship, Orthopedic Foot & Ankle Center, Columbus, OH
    • ,
  • Gregory C. Berlet, MD

      Affiliations

    • Attending Staff, Orthopedic Foot & Ankle Center, Columbus, OH; Chief Section of Foot & Ankle Surgery and Clinical Assistant Professor, Department of Orthopedics, Ohio State University, Columbus, OH
    • ,
  • Thomas H. Lee, MD

      Affiliations

    • Attending Staff, Orthopedic Foot & Ankle Center, Columbus, OH

References 

  1. Yamaguchi Y, Kubo T, Murakami T, Takahashi M, Hakamata E, Hobayashi S, et al. Bone marrow cells differentiate into wound myofibroblasts and accelerate the healing of wounds with exposed bones when combined with an occlusive dressing. Br J Dermatol. 2005;152(4):616–627
  2. Hernigou PH, Mathieu G, Poignard A, Manicom O, Beaujean F, Rouard H. Percutaneous autologous bone-marrow grafting for nonunions: surgical technique. J Bone Joint Surg. 2006;88-A(Suppl 1):322–327
  3. Chong A, Ang A, Goh J, Hui J, Lim A, Lee E, et al. Bone marrow-derived mesenchymal stem cells influence early tendon-healing in a rabbit Achilles tendon model. J Bone Joint Surg. 2007;89(1):74–81
  4. Muschler G, Boehm C, Easley K. Aspiration to obtain osteoblast progenitor cells from human bone marrow: the influence of aspiration volume. J Bone Joint Surg. 1997;79-A(11):1699–1709
  5. Schweinberger M, Roukis T. Percutaneous autologous bone-marrow harvest from the calcaneus and proximal tibia: surgical technique. J Foot Ankle Surg. 2007;46(5):411–414
  6. Schade V, Roukis T. Percutaneous bone marrow aspirate and bone graft harvesting techniques in the lower extremity. Clin Podiatr Med Surg. 2008;25(4):733–742
  7. Mendicino RA, Leonhart E, Shromoff P. Techniques for harvesting autogenous bone grafts in the lower extremity. J Foot Ankle Surg. 1996;35(5):428–435
  8. Lezcano FJ, Cagigal BP, Cantera JM. de la Pena Varela G, Blanco RF, Hernandez AV. Technical note: medial approach for proximal tibia bone graft using a manual trephine. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007;104(1):11–17
  9. Geideman W, Early JS, Brodsky J. Clinical results of harvesting autogenous cancellous graft from the ipsilateral proximal tibia for use in foot and ankle surgery. Foot Ankle Int. 2004;25(7):451–455
  10. Whitehouse MR, Lankester BJA, Winson IG, Hepple S. Bone graft harvest from the proximal tibia in foot and ankle arthrodesis surgery. Foot Ankle Int. 2006;27(11):913–916
  11. O'Keeffe RM, Riemer BL, Butterfield SL. Harvesting of autogenous cancellous bone graft from the proximal tibial metaphysis. J Orthop Trauma. 1991;5(4):469–474
  12. Mahan KT. Calcaneal donor bone grafts. J Am Podiatr Med Assoc. 1994;84(1):1–9
  13. Mahan KT. Reply to: A new modified technique for harvest of calcaneal bone graft in surgery on the foot and ankle. Foot Ankle Int. 1999;20(1):68
  14. Biddinger KR, Komenda GA, Schon LC, Myerson MS. A new modified technique for harvest of calcaneal bone grafts in surgery on the foot and ankle. Foot Ankle Int. 1998;19(5):322–326

 Disclaimer: The opinions or assertions contained herein are the private view of the author and are not to be construed as official or reflecting the views of the Department of the Army or the Department of Defense.

 Financial Disclosure: None reported.

 Conflict of Interest: None reported.

PII: S1067-2516(09)00305-6

doi: 10.1053/j.jfas.2009.07.016

Journal of Foot and Ankle Surgery
Volume 48, Issue 6 , Pages 668-671 , November 2009

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