Journal of Foot and Ankle Surgery
Volume 49, Issue 2 , Pages 123-127, March 2010

The Porcine Small Intestinal Submucosa (SIS) Patch in Foot and Ankle Reconstruction

  • Christopher Bibbo, DO, DPM, FACS, FACFAS

      Affiliations

    • Chief, Foot & Ankle Section, Department of Orthopaedics, Marshfield Clinic, Marshfield, WI
    • Corresponding Author InformationAddress correspondence to Christopher Bibbo, DO, DPM, FACS, FACFAS, Department of Orthopaedics, Marshfield Clinic, 1000 North Oak Avenue, Marshfield, WI 54449.

published online 21 December 2009.

Abstract 

We undertook a retrospective cohort study of 54 patients who underwent foot and ankle soft tissue reconstructive surgery augmented with a porcine small intestinal submucosal (SIS) patch. The mean patient age was 44 (range 17 to 68) years, there were 21 (38.89%) males in the cohort, and the mean follow-up duration was 1080 (range 365 to 1943) days. Clinical outcomes were considered excellent in 46 (85.19%) patients, good/fair in 3 (5.56%) patients, and poor in 5 (9.26%) patients; and no adverse events attributable to the xenograft were observed. Direct SIS patch failure, resulting in stretching of the repair, re-tear, or tendon stenosis, occurred in 3 (5.56%) patients, and delayed incision healing occurred in 6 (11.11%) patients. Based on our observations, we concluded that the porcine SIS xenograft, when used to augment cellular and vascular in-growth, is a viable adjunct to musculoskeletal reconstructions of the foot and ankle.

Level of Clinical Evidence: 2

Keywords: complication, outcomes, porcine, scaffold, soft tissue, tendon, xenograft

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 Financial Disclosure: None reported.

 Conflict of Interest: None reported.

PII: S1067-2516(09)00419-0

doi:10.1053/j.jfas.2009.09.004

Journal of Foot and Ankle Surgery
Volume 49, Issue 2 , Pages 123-127, March 2010