Abstract
Vitamin D is an essential, fat-soluble nutrient that is a key modulator of bone health.
Despite the gaining popularity throughout published medical studies, no consensus
has been reached regarding a serum vitamin D level that will guarantee adequate skeletal
health in a patient with an increased functional demand. The purpose of the present
investigation was to examine the serum concentrations of vitamin D in patients with
confirmed stress fractures. A total of 124 patients were included in our retrospective
cohort study. Of the 124 patients, 53 had vitamin D levels measured within 3 months
of diagnosis. An association was seen in patients with a stress fracture and vitamin
D level measured, as 44 (83.02%) of the 53 patients had a serum 25-hydroxyvitamin
D level <40 ng/mL. Although an association was seen at our institution in patients
with stress fractures and a serum vitamin D concentration <40 ng/mL, a larger and
prospective investigation is warranted to further understand the effect of vitamin
D level and stress fracture prevention in an active, nonmilitary population.
Level of Clinical Evidence
Keywords
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to The Journal of Foot and Ankle SurgeryAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- How vitamin D works on bone.Endocrinol Metab Clin North Am. 2012; 41: 557-569
- Vitamin D—a systematic literature review for the 5th edition of the Nordic nutrition recommendations.Food Nutr Res. 2013; 57: 226-271
- Resurrection of vitamin D deficiency and rickets.J Clin Invest. 2006; 116: 2062-2072
- Vitamin D and bone.Curr Osteoporos Rep. 2012; 10: 151-159
- Vitamin D: Methods of 25 hydroxyvitamin D analysis, targeting at risk populations and selecting thresholds of treatment.Clin Biochem. 2012; 45: 901-906
- Vitamin D—from essentiality to functionality.Int J Vitam Nutr Res. 2012; 82: 321-326
- Vitamin D supplementation in elderly or postmenopausal women: a 2013 update of the 2008 recommendations from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO).Curr Med Res Opin. 2013; 29: 305-313
- Prevalence of vitamin D insufficiency in Swiss teenagers with appendicular fractures: a prospective study of 100 cases.J Child Orthop. 2012; 6: 497-503
- Stress fractures in elderly patients.Int Orthop. 2012; 36: 2581-2587
- Bone mineralization defects and vitamin D deficiency: histomorphometric analysis of iliac crest bone biopsies and circulating 25-hydroxyvitamin D in 675 patients.J Bone Miner Res. 2010; 25: 305-312
- Serum 25-hydroxyvitamin D levels and stress fractures in military personnel.Am J Sports Med. 2015; 43: 2064-2072
- Calcium and vitamin D supplementation decreases incidence of stress fracture in female navy recruits.J Bone Miner Res. 2008; 23: 741-749
- High serum 25-hydroxyvitamin D is associated with a low incidence of stress fractures.J Bone Miner Res. 2011; 26: 2371-2377
- What are the dietary requirements for calcium and vitamin D.Calcif Tissue Int. 2002; 70: 83-88
- Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society Clinical Practice Guideline.J Clin Endocrinol Metab. 2011; 96: 1911-1930
- Estimated equivalency of vitamin D production from natural sun exposure versus oral vitamin D supplementation across seasons at two US latitudes.J Am Acad of Dermatol. 2010; 62: 929.e1-929.e9
The Vitamin D Council. Testing for vitamin D. Available at: http://www.vitamindcouncil.org/about-vitamin-d/testing-for-vitamin-d/#. Accessed September 2, 2014.
Article info
Publication history
Published online: September 23, 2015
Footnotes
Financial Disclosure: None reported.
Conflict of Interest: None reported.
Identification
Copyright
© 2016 American College of Foot and Ankle Surgeons. Published by Elsevier Inc. All rights reserved.
