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Case Report| Volume 49, ISSUE 2, P159.e1-159.e8, March 2010

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Clostridium septicum Necrotizing Fasciitis of the Forefoot Secondary to Adenocarcinoma of the Colon: Case Report and Review of the Literature

  • Valerie L. Schade
    Affiliations
    Fellow (PGY-5), Limb Preservation Complex Lower Extremity Surgery and Research Fellowship, Limb Preservation Service, Vascular/Endovascular Surgery Service, Department of Surgery, Madigan Army Medical Center, Tacoma, WA
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  • Thomas S. Roukis
    Correspondence
    Address correspondence to Thomas S. Roukis, DPM, PhD, FACFAS, Chief, Limb Preservation Service, Vascular/Endovascular Surgery Service, Department of Surgery; Director, Limb Preservation Complex Lower Extremity Surgery and Research Fellowship, Madigan Army Medical Center, 9040-A Fitzsimmons Drive, MCHJ-SV, Tacoma, WA 98431.
    Affiliations
    Chief, Limb Preservation Service, Vascular/Endovascular Surgery Service, Department of Surgery; Director, Limb Preservation Complex Lower Extremity Surgery and Research Fellowship, Madigan Army Medical Center, Tacoma, WA
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  • Mohamad Haque
    Affiliations
    Attending Staff, General Surgery Service, Department of Surgery, Madigan Army Medical Center, Tacoma, WA
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Published:November 30, 2009DOI:https://doi.org/10.1053/j.jfas.2009.06.007

      Abstract

      Clostridium septicum accounts for 1% of all reported clostridial infections. C septicum infections are most often nontraumatic in nature and associated with either an occult colonic or hematologic malignancy. The initial presentation of a C septicum infection can be relatively benign with rapid progression to fatality without emergent treatment. Presented is a case of necrotizing fasciitis of the forefoot caused by C septicum associated with an occult adenocarcinoma of the colon in a patient with uncontrolled diabetes. The process we used to achieve successful functional limb preservation based on rapid surgical intervention and use of a multidisciplinary approach to medical and surgical management of this patient is discussed in detail, as well as a through review of the literature regarding the association between malignancies and C septicum infections.

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