Abstract
We undertook a retrospective cohort study of 54 patients who underwent foot and ankle
soft tissue reconstructive surgery augmented with a porcine small intestinal submucosal
(SIS) patch. The mean patient age was 44 (range 17 to 68) years, there were 21 (38.89%)
males in the cohort, and the mean follow-up duration was 1080 (range 365 to 1943)
days. Clinical outcomes were considered excellent in 46 (85.19%) patients, good/fair
in 3 (5.56%) patients, and poor in 5 (9.26%) patients; and no adverse events attributable
to the xenograft were observed. Direct SIS patch failure, resulting in stretching
of the repair, re-tear, or tendon stenosis, occurred in 3 (5.56%) patients, and delayed
incision healing occurred in 6 (11.11%) patients. Based on our observations, we concluded
that the porcine SIS xenograft, when used to augment cellular and vascular in-growth,
is a viable adjunct to musculoskeletal reconstructions of the foot and ankle.
Level of Clinical Evidence
Keywords
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Article info
Publication history
Published online: December 21, 2009
Footnotes
Financial Disclosure: None reported.
Conflict of Interest: None reported.
Identification
Copyright
© 2010 American College of Foot and Ankle Surgeons. Published by Elsevier Inc. All rights reserved.
