Abstract
A number of studies have stressed the importance of platelets in acute and chronic
wound healing, although their clinical utility remains controversial. To analyze the
use of autologous platelet gel in the surgical treatment of ingrown toenails, a within-patient
clinical trial was conducted. Thirty-five healthy volunteers (70 feet) underwent surgical
treatment for bilateral ingrown hallux nails. Recovery time (days), postoperative
pain (analog chromatic scale), and inflammation (digital circumference) at 48 hours
postoperative were the outcomes of interest. Recovery time and postoperative pain
were less in the experimental group, although the differences of means were not statistically
significant. Based on these results, we suggest that local application of APG in surgical
ingrown toenail wounds may produce a slight increase in acute inflammatory phase dermal
wound healing, but it does not cause a statistically significant reduction in recovery
times or postoperative pain.
Level of Clinical Evidence
Keywords
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Article info
Publication history
Published online: June 04, 2010
Footnotes
Financial Disclosure: None reported.
Conflict of Interest: None reported.
Identification
Copyright
© 2010 American College of Foot and Ankle Surgeons. Published by Elsevier Inc. All rights reserved.