Case Report| Volume 49, ISSUE 6, P565.e5-565.e7, November 2010

The Use of Collagen Injections in the Treatment of Metatarsalgia: A Case Report

Published:September 20, 2010DOI:


      Metatarsalgia is an increasingly common condition seen in the outpatient setting. A number of conservative and surgical management options are available for this condition. We present an interesting case that was unsuccessfully treated with‘dermal filler.’ To our knowledge, we have not found any published material in peer-reviewed journals documenting the use of collagen injections in the treatment of metatarsalgia. The authors feel that the lesson learned from this case should be highlighted for other foot and ankle surgeons.

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        • Waldecker U.
        Plantar fat pad atrophy: a cause of metatarsalgia?.
        J Foot Ankle Surg. 2001; 40: 21-27
        • Gill L.H.
        Plantar fasciitis: diagnosis and conservative management.
        J Am Acad Orthop Surg. 1997; 5: 109-117
        • Ayub A.
        • Yale S.H.
        • Bibbo C.
        Common foot disorders.
        Clin Med Res. 2005; 3: 116-119
        • Bus S.A.
        • Maas M.
        • Cavanagh P.R.
        • Michels R.P.
        • Levi M.
        Plantar fat-pad displacement in neuropathic diabetic patients with toe deformity. A magnetic resonance imaging study.
        Diabetes Care. 2004; 24: 2376-2381
        • D’Ambrosia R.D.
        Conservative management of metatarsal and heel pain in the adult foot.
        Orthopedics. 1987; 10: 137-142
        • Chalmers A.C.
        • Busby C.
        • Goyert J.
        • Porter B.
        • Schulzer M.
        Metatarsalgia and rheumatoid arthritis—a randomized, single blind, sequential trial comparing 2 types of foot orthoses and supportive shoes.
        J Rheumatol. 2000; 27: 1643-1647
        • Helal B.
        Metatarsal osteotomy for metatarsalgia.
        J Bone Joint Surg (Br). 1975; 57-B: 187-192
        • O’Kane C.
        • Kilmartin T.E.
        The surgical management of central metatarsalgia.
        Foot Ankle Int. 2002; 23: 415-419
        • Balkin S.W.
        Injectable silicone and the foot: a 41-year clinical and histologic history.
        Derm Surg. 2005; 31: 1555-1560
        • Appell R.A.
        Collagen injection therapy for urinary incontinence.
        Urol Clin North Am. 1994; 21: 177-182
        • Remacle M.
        • Lawson G.
        • Delos M.
        • Jamart J.
        Correcting vocal fold immobility by autologous collagen injection for voice rehabilitation. A short-term study.
        Ann Otol Rhinol Laryngol. 1999; 108: 788-793
        • Heise H.
        • Zimmerman R.
        • Heise P.
        Temporary granulomatous inflammation following collagen implantation.
        J Craniomaxillofac Surg. 2001; 29: 238-241