Abstract
On occasion, the placement of orthopedic prosthetic components or stabilization hardware
leads to surgical site infections, in some cases presenting at a point in time distant
from the surgical procedure. Although infectious complications are the most common
etiology for surgical site pain and inflammation, malignancies can also develop around
prosthetic devices and metallic implants. When encountered, such malignancies are
most often sarcoma, but rarely B-cell non-Hodgkin’s lymphoma has also been described.
In this article, we describe what we believe to be the first published case of anaplastic
large T-cell lymphoma associated with a stainless steel fixation plate that was implanted
several years earlier for repair of a tibial fracture. Appropriate to this case, we
review the medical literature on the association of orthopedic implants with the development
of neoplasm, along with the theorized pathogenic mechanisms leading to such an association.
Level of Clinical Evidence
Keywords
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References
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Article info
Publication history
Published online: September 27, 2010
Footnotes
Financial Disclosure: None reported.
Conflict of Interest: None reported.
Identification
Copyright
© 2010 American College of Foot and Ankle Surgeons. Published by Elsevier Inc. All rights reserved.
