Abstract
Timely incorporation of bone grafts is essential to the structural rigidity in most
foot and ankle surgeries. Although bovine-based xenografts possess some of the key
features necessary for foot and ankle surgery, the studies evaluating the efficacy
of these grafts are limited. The aim of the present study was to determine the incorporation
rate of bovine-based bone grafts in foot surgery. A total of 22 patients who had undergone
reconstructive foot surgery using 31 bovine-based xenografts were identified, and
the rate of radiographic incorporation of the grafts was evaluated. A survival analysis
was used to show the trend of the incorporation of the xenografts over time. Of the
21 grafts observed for at least 12 weeks, none showed radiographic graft incorporation
by 12 weeks. The analogous numbers for 24, 36, and 48 weeks were 3 (20%) of 15, 4
(31%) of 13, and 3 (27%) of 11 grafts. A total of 19 (61.29%) of the 31 grafts studied
were never observed to have incorporated radiographically, for the entire observation
period. A Kaplan-Meier estimate revealed the median interval to graft incorporation
was 56 weeks. Compared with previous studies, which investigated the incorporation
of other types of grafts, such as autograft and allografts, we believe that xenografts
incorporate more slowly. For this reason, such grafts might not be ideal for use in
reconstructive foot surgery.
Level of Clinical Evidence
Keywords
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Article info
Publication history
Published online: October 31, 2011
Footnotes
Financial Disclosure: None reported.
Conflict of Interest: None reported.
Identification
Copyright
© 2012 American College of Foot and Ankle Surgeons. Published by Elsevier Inc. All rights reserved.
