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Self-Reported Quality of Life and Diabetic Foot Infections

  • Katherine M. Raspovic
    Affiliations
    Assistant Professor, Department of Plastic Surgery, Georgetown University School of Medicine, Washington, DC
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  • Dane K. Wukich
    Correspondence
    Address correspondence to: Dane K. Wukich, MD, Division of Foot and Ankle Surgery, Department of Orthopaedic Surgery, University of Pittsburgh School of Medicine, Roesch-Taylor Building, Suite 7300, 2100 Jane Street, Pittsburgh, PA 15203.
    Affiliations
    Professor of Orthopaedic Surgery, University of Pittsburgh School of Medicine, Medical Director, UPMC Mercy Center for Healing and Amputation Prevention, Pittsburgh, PA
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Published:August 13, 2014DOI:https://doi.org/10.1053/j.jfas.2014.06.011

      Abstract

      Foot infections in patients with diabetes mellitus (DM) are serious complications that can result in hospitalization, the need for amputation, and premature mortality. To the best of our knowledge, no published studies have specifically investigated the effect of diabetic foot infection (DFI) on patient quality of life. The aim of the present study was to compare the self-reported assessments of quality of life in patients hospitalized with DFIs with those from a group of patients without foot infections. We evaluated a study group of 47 patients who had been hospitalized with DFIs and a control group of 47 patients with DM who did not have any complaints referable to their foot or ankle. The self-reported outcomes were assessed using the Medical Outcomes Study short form 36-item health survey (SF-36) and the Foot and Ankle Ability Measurement. Patients hospitalized with DFIs had significantly reduced self-reported SF-36 scores in all 8 subscales compared with the cohort of patients with DM without foot complaints. The SF-36 physical component and mental component scores were significantly reduced in patients with DFIs, indicating a negative effect on overall health. Self-reported lower extremity function was also negatively affected with significantly lower Foot and Ankle Measurement activity of daily living and sports scores for patients with DFI. The present study has demonstrated the profoundly negative affect that moderate and severe DFIs have on self-reported quality of life, affecting both physical and mental well-being and lower extremity function.

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      References

      1. National Diabetes Fact Sheet, 2011. US Department of Health and Human Services, Centers for Disease Control and Prevention, Available at: http://www.cdc.gov/diabetes/pubs/pdf/ndfs_2011.pdf, Accessed June 10, 2013.

        • Lavery L.A.
        • Armstrong D.G.
        • Wunderlich R.P.
        • Mohler M.J.
        • Wendel C.S.
        • Lipsky B.A.
        Risk factors for foot infections in individuals with diabetes.
        Diabetes Care. 2006; 29: 1288-1293
        • Hobizal K.B.
        • Wukich D.K.
        Diabetic foot infections: current concept review.
        Diabetic Foot Ankle. 2012; 3
        • Wukich D.K.
        • Hobizal K.B.
        • Brooks M.M.
        Severity of diabetic foot infection and rate of limb salvage.
        Foot Ankle Int. 2013; 34: 351-358
        • Dhawan V.
        • Spratt K.F.
        • Pinzur M.S.
        • Baumhauer J.
        • Rudicel S.
        • Saltzman C.L.
        Reliability of AOFAS diabetic foot questionnaire in Charcot arthropathy: stability, internal consistency, and measurable difference.
        Foot Ankle Int. 2005; 26: 717-731
        • Goodridge D.
        • Trepman E.
        • Embil J.M.
        Health-related quality of life in diabetic patients with foot ulcers: literature review.
        J Wound Ostomy Continence Nurs. 2005; 32: 368-377
        • Goodridge D.
        • Trepman E.
        • Sloan J.
        • Guse L.
        • Strain L.A.
        • McIntyre J.
        • Embil J.M.
        Quality of life of adults with unhealed and healed diabetic foot ulcers.
        Foot Ankle Int. 2006; 27: 274-280
        • Ware Jr., J.E.
        • Kosinski M.
        • Keller S.D.
        SF-36® Physical and Mental Health Summary Scales: A User's Manual.
        The Health Institute, Boston1994
        • Ware Jr., J.E.
        • Sherbourne C.D.
        The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection.
        Med Care. 1992; 30: 473-483
        • Hogg F.R.
        • Peach G.
        • Price P.
        • Thompson M.M.
        • Hinchliffe R.J.
        Measures of health-related quality of life in diabetes-related foot disease: a systematic review.
        Diabetologia. 2012; 55: 552-565
        • Meijer J.W.
        • Trip J.
        • Jaegers S.M.
        • Links T.P.
        • Smits A.J.
        • Groothoff J.W.
        • Eisma W.H.
        Quality of life in patients with diabetic foot ulcers.
        Disabil Rehabil. 2001; 23: 336-340
        • Nabuurs-Franssen M.H.
        • Huijberts M.S.
        • Nieuwenhuijzen Kruseman A.C.
        • Willems J.
        • Schaper N.C.
        Health-related quality of life of diabetic foot ulcer patients and their caregivers.
        Diabetologia. 2005; 48: 1906-1910
        • Pakarinen T.K.
        • Laine H.J.
        • Maenpaa H.
        • Mattila P.
        • Lahtela J.
        Long-term outcome and quality of life in patients with Charcot foot.
        Foot Ankle Surg. 2009; 15: 187-191
        • Pinzur M.S.
        • Evans A.
        Health-related quality of life in patients with Charcot foot.
        Am J Orthop. 2003; 32: 492-496
        • Ribu L.
        • Hanestad B.R.
        • Moum T.
        • Birkeland K.
        • Rustoen T.
        A comparison of the health-related quality of life in patients with diabetic foot ulcers, with a diabetes group and a nondiabetes group from the general population.
        Qual Life Res. 2007; 16: 179-189
        • Kivlan B.R.
        • Martin R.L.
        • Wukich D.K.
        Responsiveness of the foot and ankle ability measure (FAAM) in individuals with diabetes.
        Foot (Edinb). 2011; 21: 84-87
        • Martin R.L.
        • Hutt D.M.
        • Wukich D.K.
        Validity of the Foot and Ankle Ability Measure (FAAM) in diabetes mellitus.
        Foot Ankle Int. 2009; 30: 297-302
        • Martin R.L.
        • Irrgang J.J.
        • Burdett R.G.
        • Conti S.F.
        • Van Swearingen J.M.
        Evidence of validity for the Foot and Ankle Ability Measure (FAAM).
        Foot Ankle Int. 2005; 26: 968-983
        • Wukich D.K.
        • Pearson K.T.
        Self-reported outcomes of trans-tibial amputations for non-reconstructable Charcot neuroarthropathy in patients with diabetes: a preliminary report.
        Diabetic Med. 2013; 30: e87-e90
        • Lipsky B.A.
        • Berendt A.R.
        • Cornia P.B.
        • Pile J.C.
        • Peters E.J.
        • Armstrong D.G.
        • Deery H.G.
        • Embil J.M.
        • Joseph W.S.
        • Karchmer A.W.
        • Pinzur M.S.
        • Senneville E.
        • Infectious Diseases Society of America
        2012 Infectious Diseases Society of America clinical practice guideline for the diagnosis and treatment of diabetic foot infections.
        Clin Infect Dis. 2012; 54: e132-e173
        • Suder N.C.
        • Wukich D.K.
        Prevalence of diabetic neuropathy in patients undergoing foot and ankle surgery.
        Foot Ankle Spec. 2012; 5: 97-101
        • Boutoille D.
        • Feraille A.
        • Maulaz D.
        • Krempf M.
        Quality of life with diabetes-associated foot complications: comparison between lower-limb amputation and chronic foot ulceration.
        Foot Ankle Int. 2008; 29: 1074-1078
        • Willrich A.
        • Pinzur M.
        • McNeil M.
        • Juknelis D.
        • Lavery L.
        Health related quality of life, cognitive function, and depression in diabetic patients with foot ulcer or amputation: a preliminary study.
        Foot Ankle Int. 2005; 26: 128-134
        • Richard J.L.
        • Lavigne J.P.
        • Got I.
        • Hartemann A.
        • Malgrange D.
        • Tsirtsikolou D.
        • Baleydier A.
        • Senneville E.
        Management of patients hospitalized for diabetic foot infection: results of the French OPIDIA study.
        Diabetes Metab. 2011; 37: 208-215
        • Raspovic K.M.
        • Wukich D.K.
        Self-reported quality of life in patients with diabetes: a comparison of patients with and without Charcot neuroarthropathy.
        Foot Ankle Int. 2014; 35: 195-200
        • Sochocki M.P.
        • Verity S.
        • Atherton P.J.
        • Huntington J.L.
        • Sloan J.A.
        • Embil J.M.
        • Trepman E.
        Health related quality of life in patients with Charcot arthropathy of the foot and ankle.
        Foot Ankle Surg. 2008; 14: 11-15