Abstract
Chondrolipoma is an extremely rare variant of lipoma with cartilaginous metaplasia.
The presence of nonlipomatous components can lead to a variety of entities in the
differential diagnosis from the radiologic findings. We describe an unusual case of
a chondrolipoma occurring in the right ankle of a 9-year-old female. Physical examination
showed a 3.5-cm, elastic-hard, poorly mobile, nontender mass adherent to the Achilles
tendon. Plain radiographs revealed a faintly calcified soft tissue mass without bone
involvement. Magnetic resonance imaging showed a well-defined mass with 2 components
with heterogeneous signal intensity, suggesting the coexistence of a fatty area and
another nonlipomatous component. Marginal excision of the tumor was performed. Histologically,
the tumor was composed of mature adipose tissue studded with islands of mature hyaline
cartilage. Based on these findings, the tumor was diagnosed as a chondrolipoma. The
patient had no evidence of local recurrence within 9 months of follow-up. To the best
of our knowledge, this is the first case of chondrolipoma originating from the ankle
in a child.
Level of Clinical Evidence
Keywords
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to The Journal of Foot and Ankle SurgeryAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Chondrolipoma of the breast: case report and a review of literature.Breast. 2006; 15: 425-426
- Chondrolipoma: report of a rare intra oral variant with review of histiogenetic concepts.J Oral Maxillofac Pathol. 2014; 18: 276-280
- Chondrolipoma in the palm of a child: sonographic and MR findings.Clin Imaging. 2004; 28: 206-208
- Intestinal chondrolipoma: uncommon cause of bowel obstruction.J Pediatr Surg. 2007; 42: e21-e23
- Giant chondrolipoma of the tongue in a 14-year-old child with mandibular hypertrophy: isolated lesion or regional overgrowth syndrome.Int J Oral Maxillofac Surg. 2012; 41: 261-264
- Histopathology of rare chondroosteoblastic metaplasia in benign lipomas.Pathol Res Pract. 1989; 184: 437-443
- Chondrolipoma of the popliteal fossa and Japanese reports.J Dermatol. 2006; 33: 202-206
- Immunohistochemical study of chondrolipoma: possible importance of transforming growth factor (TGF)-betas, latent TGF-beta binding protein-1 (LTBP-1), and bone morphogenetic protein (BMP) for chondrogenesis in lipoma.J Dermatol. 2003; 30: 189-195
- Osteolipoma: radiological, pathological, and cytogenetic analysis of three cases.Skeletal Radiol. 2012; 41: 237-244
- Intermuscular chondrolipoma of the thigh: the diagnostic way of a rare entity.Pathol Res Pract. 2003; 199: 503-507
- Chondrolipoma of the hand: a case report.Acta Orthop Belg. 2004; 70: 495-497
- Chondrolipoma of the toe.J Dermatol. 2007; 34: 570-572
- Chondrolipoma in the pelvic cavity: a case report.Korean J Radiol. 2008; 9: 563-567
- Chondro-osseous differentiation in fat tissue tumors: magnetic resonance imaging with pathological correlation.Skeletal Radiol. 2000; 29: 459-465
- Contributions of cytogenetics and molecular cytogenetics to the diagnosis of adipocytic tumors.J Biomed Biotechnol. 2011; 2011: 524067
- Spectrum of fat-containing soft-tissue masses at MR imaging: the common, the uncommon, the characteristic, and the sometimes confusing.Radiographics. 2016; 36: 753-766
- MRI features of lipoblastoma: differentiating from other palpable lipomatous tumor in pediatric patients.Clin Imaging. 2010; 34: 453-457
- Updates on the cytogenetics and molecular cytogenetics of benign and intermediate soft tissue tumors.Oncol Lett. 2013; 5: 12-18
- Chondroid lipoma: correlation of imaging findings and histopathology of an unusual benign lesion.Skeletal Radiol. 2004; 33: 670-673
- Deep-seated ordinary and atypical lipomas: histopathology, cytogenetics, clinical features, and outcome in 215 tumours of the extremity and trunk wall.J Bone Joint Surg Br. 2008; 90: 929-933
Article info
Publication history
Published online: June 13, 2017
Footnotes
Financial Disclosure: None reported.
Conflict of Interest: None reported.
Identification
Copyright
© 2017 by the American College of Foot and Ankle Surgeons. All rights reserved.
