Advertisement
Research Article| Volume 57, ISSUE 2, P289-295, March 2018

Risk Factors and Frequency of Ingrown Nails in Adult Diabetic Patients

Published:January 10, 2018DOI:https://doi.org/10.1053/j.jfas.2017.10.006

      Abstract

      The present study evaluated the properties of nails, frequency of ingrown nails in patients with type 2 diabetes mellitus (DM), risk factors for developing ingrown nails, and effect of diabetic polyneuropathy and vasculopathy on the development and outcome of ingrown nails. Our 6-month epidemiologic prospective study included 300 patients with type 2 DM attending a DM outpatient clinic for routine examinations. The general characteristics and foot changes of the study population were investigated. Diabetic polyneuropathy and vasculopathy were evaluated using a biothesiometer, monofilament tests, and arterial Doppler ultrasonography. The frequency of ingrown nails was 13.6%. Multivariate analysis with logistic regression showed that body mass index (odds ratio [OR] 1.077, 95% confidence interval [CI] 1.007 to 1.15; p = .03), previous trauma (OR 2.828, 95% CI 1.017 to 7,867, p = .042), a weak dorsalis pedis pulse (OR 2.72, 95% CI 1.17 to 6.30, p = .02), trimming type (OR 2.3, 95 CI 1.06 to 4.98), p = .35), onychogryphosis (OR 9.036, 95% CI 2.34 to 34.87, p = .001), and subungual hyperkeratosis (OR 4.3, 95% CI 1.99 to 9.3, p = .001) were predictive variables for ingrown nails in our population. The incidence of onychomycosis was significantly greater in patients with ingrown nails (p = .032) than in patients without ingrown nails. The nail curvature ratio was greater in the patients with ingrown nails than in the group with normal nails. Arterial Doppler ultrasound examinations showed peripheral arterial disease in 19 patients (46.9%) with ingrown nails. The prevalence of ingrown nails was greater in the patients with DM than in the healthy population. Our results indicate that nail type, nail morphology, and diabetic vasculopathy affect the formation and evolution of ingrown nails.

      Level of Clinical Evidence

      Keywords

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to The Journal of Foot and Ankle Surgery
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Litzelman D.K.
        • Marriott D.J.
        • Vinicor F.
        Independent physiological predictors of foot lesions in patients with NIDDM.
        Diabetes Care. 1997; 20: 1273-1278
        • Chuback J.
        • Embil J.M.
        • Sellers E.
        • Trepman E.
        • Cheang M.
        • Dean H.
        Foot abnormalities in Canadian Aboriginal adolescents with type 2 diabetes.
        Diabet Med. 2007; 24: 747-752
        • Muniz E.C.
        • Rocha R.M.
        • Reis M.L.
        • Santos V.L.
        • Grossi S.A.
        Neuropathic and ischemic changes of the foot in Brazilian patients with diabetes.
        Ostomy Wound Manage. 2003; 49: 60-70
        • Holewski J.J.
        • Moss K.M.
        • Stess R.M.
        • Graf P.M.
        • Grunfeld C.
        Prevalence of foot pathology and lower extremity complications in a diabetic outpatient clinic.
        J Rehabil Res Dev. 1989; 26: 35-44
        • Newcombe R.G.
        Two-sided confidence intervals for the single proportion: comparison of seven methods.
        Stat Med. 1998; 17: 857-872
        • Pearson H.J.
        • Bury R.N.
        • Wapples J.
        • Watkin D.F.
        Ingrowing toenails: is there a nail abnormality? A prospective study.
        J Bone Joint Surg Br. 1987; 69: 840-842
        • Levy L.A.
        Prevalence of chronic podiatric conditions in the US. National Health Survey 1990.
        J Am Podiatr Med Assoc. 1992; 82: 221-223
        • Langford D.T.
        • Burke C.
        • Robertson K.
        Risk factors in onychocryptosis.
        Br J Surg. 1989; 76: 45-48
        • Lloyd-Davies R.W.
        Ingrowing toenails.
        BMJ. 1963; 2: 1653
        • Ganesh J.
        • Viswanathan V.
        Management of diabetic hypertensives.
        Indian J Endocrinol Metab. 2011; 15: S374-S379
        • Leitao C.B.
        • Canani L.H.
        • Silveiro S.P.
        • Gross J.L.
        Ambulatory blood pressure monitoring and type 2 diabetes mellitus.
        Arq Bras Cardiol. 2007; 89: 315-321
        • Penna G.L.
        • Garbero Rde F.
        • Neves M.F.
        • Oigman W.
        • Bottino D.A.
        • Bouskela E.
        Treatment of essential hypertension does not normalize capillary rarefaction.
        Clinics (Sao Paulo). 2008; 63: 613-618
        • Siegle R.J.
        • Stewart R.
        Recalcitrant ingrowing nails: surgical approaches.
        J Dermatol Surg Oncol. 1992; 18: 744-752
        • Zuber T.J.
        • Pfenninger J.L.
        Management of ingrown toenails.
        Am Fam Physician. 1995; 52: 181-190
        • Xu B.
        • Yang C.Z.
        • Wu S.B.
        • Zhang D.
        • Wang L.N.
        • Xiao L.
        • Chen Y.
        • Wang C.R.
        • Tong A.
        • Zhou X.F.
        • Li X.H.
        • Guan X.H.
        Risk factors for lower extremity amputation in patients with diabetic foot.
        Zhonghua Nei Ke Za Zhi. 2017; 56: 24-28
        • Hamada N.
        • Ikuta Y.
        • Ikeda A.
        Arteries to the great and second toes based on three-dimensional analysis of 100 cadaveric feet.
        Surg Radiol Anat. 1993; 15: 187-192
        • Van Tongeren R.B.
        • Bastiaansen A.J.
        • Van Wissen R.C.
        • Le Cessie S.
        • Hamming J.F.
        • Van Bockel J.H.
        A comparison of the Doppler-derived maximal systolic acceleration versus the ankle-brachial pressure index or detecting and quantifying peripheral arterial occlusive disease in diabetic patients.
        J Cardiovasc Surg (Torino). 2010; 51: 391-398
        • Aboyans V.
        • Ho E.
        • Denenberg J.O.
        • Ho L.A.
        • Natarajan L.
        • Criqui M.H.
        The association between elevated ankle systolic pressures and peripheral occlusive arterial disease in diabetic and nondiabetic subjects.
        J Vasc Surg. 2008; 48: 1197-1203
        • Akram J.
        • Aamir A.U.
        • Basit A.
        • Qureshi M.S.
        • Mehmood T.
        • Shahid S.K.
        • Khoso I.A.
        • Ebrahim M.A.
        • Omair A.
        Prevalence of peripheral arterial disease in type 2 diabetics in Pakistan.
        J Pak Med Assoc. 2011; 61: 644-648
        • Li L.
        • Yu H.
        • Zhu J.
        • Wu X.
        • Liu F.
        • Zhang F.
        • Li Q.
        • Wu S.
        • Bao Y.
        • Jia W.
        The combination of carotid and lower extremity ultrasonography increases the detection of atherosclerosis in type 2 diabetes patients.
        J Diabetes Complications. 2012; 26: 23-28
        • Armstrong D.G.
        • Lavery L.A.
        • Vela S.A.
        • Quebedeaux T.L.
        • Fleischli J.G.
        Choosing a practical screening instrument to identify patients at risk for diabetic foot ulceration.
        Arch Intern Med. 1998; 158: 289-292
        • Baran R.
        Nail surgery.
        in: Klaus Wolff L.A.G. Katz S. Gılchrest B. Paller A.S. Leffell D.J. Fitzpatrick's Dermatology in General Medicine. McGraw Hill Medical, New York2007: 2320-2329
        • Johnson M.
        • Comaish J.S.
        • Shuster S.
        Nail is produced by the normal nail bed: a controversy resolved.
        Br J Dermatol. 1991; 125: 27-29
        • Haneke E.
        Surgical treatment of ingrowing toenails.
        Cutis. 1986; 37: 251-256
        • Ikard R.W.
        Onychocryptosis.
        J Am Coll Surg. 1998; 187: 96-102
        • Keefe M.
        • Chapman R.S.
        • Peden N.R.
        Ingrowing fingernails: an unusual complication of acromegaly successfully treated by conservative means.
        Clin Exp Dermatol. 1987; 12: 343-344
        • Johnson M.
        • Shuster S.
        Determinants of nail thickness and length.
        Br J Dermatol. 1994; 130: 195-198
        • Weaver T.D.
        • Jespersen D.L.
        Multiple onychocryptosis following treatment of onychomycosis with oral terbinafine.
        Cutis. 2000; 66: 211-212
        • Connelley Jr, L.K.
        • Dinehart S.M.
        • McDonald R.
        Onychocryptosis associated with the treatment of onychomycosis.
        J Am Podiatr Med Assoc. 1999; 89: 424-426
        • Bonifaz A.
        • Paredes V.
        • Fierro L.
        Onychocryptosis as consequence of effective treatment of dermatophytic onychomycosis.
        J Eur Acad Dermatol Venereol. 2007; 21: 699-700
        • Gutierrez-Mendoza D.
        • De Anda Juarez M.
        • Avalos V.F.
        • Martinez G.R.
        • Dominguez-Cherit J.
        “Cotton nail cast”: a simple solution for mild and painful lateral and distal nail embedding.
        Dermatol Surg. 2015; 41: 411-414
        • d'Almeida L.F.
        • Nakamura R.
        Onychocryptosis treatment pearls: the “rolled cotton padding” maneuver and the “artificial resin nail” technique.
        Dermatol Surg. 2016; 42: 434-436
        • Sano H.
        • Ogawa R.
        Clinical evidence for the relationship between nail configuration and mechanical forces.
        Plast Reconstr Surg Glob Open. 2014; 2: e115
        • Sano H.
        • Shionoya K.
        • Ogawa R.
        Finger nail configuration is influenced by mechanical forces on finger pads.
        J Dermatol. 2013; 40: 1056-1057
        • Lloyd-Davies R.W.
        • Brill G.C.
        The aetiology and outpatient management of ingrowing toenails.
        Br J Surg. 1963; 50: 592-597
        • Issa M.M.
        • Tanner W.A.
        Approach to ingrowing toenails: the wedge resection/segmental phenolization combination treatment.
        Br J Surg. 1988; 75: 181-183
        • Scher R.K.
        Toenail disorders.
        Clin Dermatol. 1983; 1: 114-124
        • Tanzi E.L.
        • Scher R.K.
        Managing common nail disorders in active patients and athletes.
        Phys Sportsmed. 1999; 27: 35-47
        • Tlougan B.E.
        • Mancini A.J.
        • Mandell J.A.
        • Cohen D.E.
        • Sanchez M.R.
        Skin conditions in figure skaters, ice-hockey players and speed skaters: part II—cold-induced, infectious and inflammatory dermatoses.
        Sports Med. 2011; 41: 967-984
        • Jenkins D.W.
        • Cooper K.
        • O'Connor R.
        • Watanabe L.
        • Wills C.
        Prevalence of podiatric conditions seen in special olympics athletes: structural, biomechanical and dermatological findings.
        Foot (Edinb). 2011; 21: 15-25
        • Pico A.M.
        • Verjano E.
        • Mayordomo R.
        Relation between nail consistency and incidence of ingrown toenails in young male runners.
        J Am Podiatr Med Assoc. 2017; 107: 137-143
        • Ross W.R.
        Treatment of the ingrown toenail and a new anesthetic method.
        Surg Clin North Am. 1969; 49: 1499-1504
        • Ozdemir E.
        • Bostanci S.
        • Ekmekci P.
        • Gurgey E.
        Chemical matricectomy with 10% sodium hydroxide for the treatment of ingrowing toenails.
        Dermatol Surg. 2004; 30: 26-31
        • Gunal I.
        • Kosay C.
        • Veziroglu A.
        • Balkan Y.
        • Ilhan F.
        Relationship between onychocryptosis and foot type and treatment with toe spacer: a preliminary investigation.
        J Am Podiatr Med Assoc. 2003; 93: 33-36
        • Cordoba-Fernandez A.
        • Montano-Jimenez P.
        • Cohena-Jimenez M.
        Relationship between the presence of abnormal hallux interphalangeal angle and risk of ingrown hallux nail: a case control study.
        BMC Musculoskelet Disord. 2015; 16: 301
        • Majcen M.E.
        • Wilfinger C.C.
        • Pilhatsch A.
        Interpretation of radiologic abnormalities in patients with chronically infected ingrown toenails with regard to a possible exogenic osteomyelitis.
        J Pediatr Surg. 2009; 44: 2179-2183
        • Cox H.A.
        • Jones R.O.
        Direct extension osteomyelitis secondary to chronic onychocryptosis: three case reports.
        J Am Podiatr Med Assoc. 1995; 85: 321-324
        • Ceilley R.I.
        • Collison D.W.
        Matricectomy.
        J Dermatol Surg Oncol. 1992; 18: 728-734
        • Letha Y.G.
        Common sports injuries of the foot and ankle seen in children and adolescents.
        Orthop Clin North Am. 1994; 25: 83-93