Abstract
Diabetes mellitus is a known risk factor for the development of multiple subtypes
of dementia and mild cognitive impairment. Recent research identifies a cause-specific
diabetes-related dementia with a unique set of characteristics. Currently, there is
no standard cognitive assessment battery recommended to specifically assess dementia
that is a direct consequence of chronic diabetes, and some evaluations have been used
for decades with minimal revisions, regardless of appropriateness. We performed a
systematic review of the dementia/cognition evaluation methods most commonly used
in the literature for assessing diabetic patients and identified which cognitive domains
are typically assessed in this setting, and whether cognitive changes were more reflective
of a vascular pathology, Alzheimer's pathology, or something else entirely. Search
results yielded 1089 articles. After screening for appropriateness, a total of 11
full-text articles were assessed. In general, subjects in the reviewed studies were
assessed using a variety of testing methods, examining different combinations of cognitive
domains. A standard, clear definition of which cognitive domains are the most important
to assess in diabetic patients is needed in order to determine what combination of
assessment tools are most pertinent. Given the growing subset of the US population,
careful reconsideration of cognitive assessment methods is needed to create self-care
plans that take into account a specific collection of cognitive challenges for those
with diabetes.
Level of Clinical Evidence
Keywords
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Article info
Publication history
Published online: November 14, 2021
Footnotes
Financial Disclosure: This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.
Conflict of Interest: None reported.
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