Abstract
Bone marrow stimulation (BMS) is indicated for patients who have symptomatic osteochondral
lesions of the talus (OLT). Despite differences in ankle biomechanics and cartilage
morphology between men and women, there is scant evidence examining whether these
differences affect surgical outcomes. The purpose of this study was to compare the
outcomes in men and women following BMS for OLTs. A retrospective analysis comparing
female and male patients treated with BMS for OLT between 2007 and 2015 was performed.
Clinical outcomes were evaluated using the Foot and Ankle Outcome Scores (FAOS) and
Short-Form 12 (SF-12). Magnetic resonance imaging at final follow-up was evaluated
with the modified magnetic resonance observation of cartilage repair tissue score.
Thirty-one females and 38 males were included. In female patients, the mean FAOS pain
score improved from 60 ± 16 preoperatively to 84 ± 8.9 at 1- to 2-year follow-up (p < .01), and then decreased to 80±13 at final follow-up at 3-4 years. In male patients,
the mean FAOS pain score improved from 65±17 preoperatively to 83±9.2 at 1-2 year
follow-up (p < .01), and then decreased to 76±14.6 at final follow-up at 3-4 years. Lateral lesions
were more common in male patients. Medial lesions were more common in female patients.
The outcomes following BMS in both female and male patients were good with no significant
differences at short-term follow-up. FAOS scores in male patients were more likely
to decrease after 1 to 2 years postsurgery, implying a possibly faster decline than
in female patients.
Level of Clinical Evidence
Keywords
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Article info
Publication history
Published online: April 28, 2022
Footnotes
Financial Disclosure: None reported.
Conflict of Interest: Dr John G. Kennedy is a consultant for Arteriocyte, Inc and Arthrex Inc; is a board member for the International Society for Cartilage Repair of the Ankle, American Orthopaedic Foot and Ankle Society Awards and Scholarships Committee, International Cartilage Repair Society finance board. Dr Gino M.M.J. Kerkhoffs is a consultant for Arthrex Inc and is a board member of the International Society for Cartilage Repair of the Ankle. Dr Arianna Gianakos, Emilie Williamson, Nathaniel Mercer have no conflicts to disclose.
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